From: Mouwenda, Y.D., et al (2021), “Characterization of T cell responses to co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in healthy adults in Gabon”, PLoS Neglected Tropical Diseases 15:10. https://doi.org/10.1371/journal.pntd.0009732 We all know how vaccines work. You take something from the pathogen into your body, triggering your body’s immune response to fight it off. Then, …
Tag Archives: medicine
Are bigger doses better? Finding new ways to fight worms
From: “Efficacy of single versus four repeated doses of praziquantel against Schistosoma mansoni infection in school-aged children from Côte d’Ivoire based on Kato-Katz and POC-CCA: An open-label, randomised controlled trial (RePST)”, P.T. Hoekstra, M. Casacuberta-Partal, L. van Lieshout et al (2020), PLoS Neglected Tropical Diseases https://doi.org/10.1371/journal.pntd.0008189 Schistosoma is a parasitic flatworm (more specifically, a trematode …
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Predicting and preventing the next Zika outbreak
From: “Impact of age-specific immunity on the timing and burden of the next Zika virus outbreak”, M.J. Counotte, C.L. Althaus, N. Low, J. Riou (2019), PLoS Neglected Tropical Diseases 13(12) https://doi.org/10.1371/journal.pntd.0007978 Zika Virus (ZIKV) is one of several mosquito-borne viruses of the flavivirus family. It was first identified as a distinct from other viruses in …
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All the small things: how good teamwork can make a big difference
From: “The division of labour between community medicine distributors influences the reach of mass drug administration: A cross-sectional study in rural Uganda”, G.F. Chami, N.B. Kabatereine, E.M. Tukahebwa (2019), PLos Neglected Tropical Diseases 13:9 https://doi.org/10.1371/journal.pntd.0007685 One under-celebrated area in medical studies is working out how best to get drugs and vaccines to at-risk communities. You …
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